Identification | Back Directory | [Name]
Germacr-1(10)-ene-5,8-dione | [CAS]
13657-68-6 | [Synonyms]
Curdione Curdione, >99% Curcuma two ketone curcumae rhizoma P.E Curcuma Tuber Extract Curdione ((+)-Curdione) Zedoary turmeric extract AaruginousTurmericRhizome Germacr-1(10)-ene-5,8-dione 6,10-Dimethyl-3-isopropyl-6-cyclodecene-1,4-dione Curdione, 98%, from Curcuma zedoaria (Christm.) Rosc (3S,6E,10S)-6,10-Dimethyl-3-propan-2-ylcyclodec-6-ene-1,4-dione 6-Cyclodecene-1,4-dione, 6,10-dimethyl-3-(1-methylethyl)-, (3S,6E,10S)- | [Molecular Formula]
C15H24O2 | [MDL Number]
MFCD28977990 | [MOL File]
13657-68-6.mol | [Molecular Weight]
236.35 |
Hazard Information | Back Directory | [Chemical Properties]
Colorless prismatic crystal (anhydrous ethanol), melting point 61~62℃, [α]25D+26°(c=1, chloroform), easily soluble in ether and chloroform, slightly soluble in petroleum ether. | [Uses]
Curdione can be used for content determination, identification and pharmacological experiments, etc. Pharmacological and pharmacological effects: It has obvious inhibitory effect on mouse sarcoma 37, mouse cervical cancer U14 and mouse Ehrlich ascites cancer, and can make cancer cells cross necrosis. Ehrlich ascites carcinoma treated with this product can successfully obtain active immunity in mice. It has good curative effect in clinical treatment of cervical cancer. | [Definition]
ChEBI: Curdione is a germacrane sesquiterpenoid. | [Biological Activity]
Curdione is a sesquiterpenoid substance isolated from Curcuma zedoary, with high biological activity, which has the effect of inhibiting platelet aggregation and resisting thrombosis. |
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