| Identification | Back Directory | [Name]
ranaconitine | [CAS]
1360-76-5 | [Synonyms]
ranaconitine
Ranaconitine（85%）
7-Hydroxylappaconitine
O4-(2-Acetamidobenzoyl)ranaconine
4-[2-(Acetylamino)benzoyloxy]-20-ethyl-1α,14α,16β-trimethoxyaconitane-7,8,9-triol
20-Ethyl-1α,14α,16β-trimethoxyaconitane-4,7,8,9-tetrol 4-[2-(acetylamino)benzoate]
Aconitane-4,7,8,9-tetrol, 20-ethyl-1,14,16-trimethoxy-, 4-[2-(acetylamino)benzoate], (1α,14α,16β)-
(1alpha,14alpha,16beta)-Aconitane-4,7,8,9-tetrol 20-ethyl-1,14,16-trimethoxy-4-[2-(acetylamino)benzoate] | [Molecular Formula]
C32H44N2O9 | [MDL Number]
MFCD11040788 | [MOL File]
1360-76-5.mol | [Molecular Weight]
600.705 |
| Chemical Properties | Back Directory | [Occurrence]
An aconitine alkaloid, ranaconitine occurs in the ethanolic extract of the Bulgarian plant
Aconitum ranunculaefolium. It forms colourless needles when crystallized from EtOH and
is dextrorotatory with a specific rotation of [α]D +33.2° (c 0.5, CHCI3 ). Hydrolysis with
5% KOH furnishes ranaconine, C23H37NO7 , m.p. 107-109°C and N-acetylanthranilic
acid. | [Melting point ]
132-134℃ | [Boiling point ]
758.9±60.0 °C(Predicted) | [density ]
1.39 | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:4): 0.2 mg/ml; DMSO: 10 mg/ml; Ethanol: 1 mg/ml | [form ]
A solid | [pka]
12.08±0.70(Predicted) |
| Hazard Information | Back Directory | [Uses]
Ranaconitine is an important diterpenoid alkaloid from Aconitum sinomontanum and displayspotential anti-inflammatory analgesic activity as well as antagonism and modulation of voltage-gated Na+ channels. | [Definition]
ChEBI: S-(2-aminoethyl)isothiourea is an imidothiocarbamic ester. | [storage]
Store at -20°C |
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