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ChemicalBook--->CAS DataBase List--->1357920-84-3

1357920-84-3

1357920-84-3 Structure

1357920-84-3 Structure
IdentificationBack Directory
[Name]

Belizatinib
[CAS]

1357920-84-3
[Synonyms]

TSR-011
CS-2493
Belizatinib
Belizatinib (TSR011)
TSR011; TSR011; TSR 011; BELIZATINIB
Benzamide, 4-fluoro-N-[6-[[4-(1-hydroxy-1-methylethyl)-1-piperidinyl]methyl]-1-[cis-4-[[(1-methylethyl)amino]carbonyl]cyclohexyl]-1H-benzimidazol-2-yl]-
[Molecular Formula]

C33H44FN5O3
[MDL Number]

MFCD31728490
[MOL File]

1357920-84-3.mol
[Molecular Weight]

577.73
Chemical PropertiesBack Directory
[density ]

1.27±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMF:30.0(Max Conc. mg/mL);51.93(Max Conc. mM)
DMSO:143.33(Max Conc. mg/mL);248.08(Max Conc. mM)
Ethanol:65.0(Max Conc. mg/mL);112.5(Max Conc. mM)
[form ]

A crystalline solid
[pka]

12.55±0.43(Predicted)
[color ]

White to off-white
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Description]

Belizatinib, also known as TSR-011, is an oral inhibitor of ALK and TRK.
[Uses]

Belizatinib is used in treating diseases via targeted modulation of gene signaling networks.
[storage]

Store at -20°C
Spectrum DetailBack Directory
[Spectrum Detail]

Belizatinib(1357920-84-3)1HNMR
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