Identification | Back Directory | [Name]
4-P-PDOT | [CAS]
134865-74-0 | [Synonyms]
AH-024 4-P-PDOT 4-PHENYL-2-PROPIONAMIDOTETRALIN N-(4-phenyl-1,2,3,4-tetrahydronaphthalen-2-yl)propanamide N-(4-Phenyl-1,2,3,4-tetrahydronaphthalen-2-yl)propionamide Propanamide, N-(1,2,3,4-tetrahydro-4-phenyl-2-naphthalenyl)- 4-P-PDOT; 4PPDOT; 4P-PDOT; AH-024; 4-PHENYL-2- PROPIONAMIDOTETRALIN. | [Molecular Formula]
C19H21NO | [MDL Number]
MFCD00901545 | [MOL File]
134865-74-0.mol | [Molecular Weight]
279.38 |
Chemical Properties | Back Directory | [Melting point ]
166 °C | [Boiling point ]
480.1±45.0 °C(Predicted) | [density ]
1.11±0.1 g/cm3(Predicted) | [storage temp. ]
Store at RT | [solubility ]
Soluble in DMSO > 10 mM | [form ]
powder | [pka]
15.87±0.40(Predicted) | [color ]
white to beige |
Hazard Information | Back Directory | [Uses]
4-P-PDOT is a MT2 melatonin receptor ligand. | [Definition]
ChEBI: N-(4-phenyl-1,2,3,4-tetrahydronaphthalen-2-yl)propanamide is a member of tetralins. | [Biological Activity]
Melatonin receptor antagonist, >300-fold selective for the MT 2 (vs MT 1 ) subtype. | [Biochem/physiol Actions]
4-P-PDOT is a slelctive MT2 melatonin receptor antagonist 300 fold selective for MT2 (MEL-1B-R) vs MT1 (MEL-1A-R) melatonin receptor subtype. |
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BOC Sciences
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1-631-485-4226; 16314854226 |
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https://www.bocsci.com |
Company Name: |
Sigma-Aldrich
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021-61415566 800-8193336 |
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https://www.sigmaaldrich.cn |
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