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ChemicalBook--->--->


IdentificationBack Directory
[CAS]

1345810-21-0
[Molecular Formula]

C18H27BCl2N2O4
[Molecular Weight]

417.13
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[solubility ]

DMSO: soluble
[form ]

A solid
Hazard InformationBack Directory
[Uses]

CB 1158 is a potent arginase inhibitor. CB-1158 has the potential for anti-tumor activity in renal cell cancer, breast cancer, non-small cell lung cancer, acute myeloid leukemia, and other tumor types where arginase-secreting MDSCs are known to play an immunosuppressive role. CB-1158 may also have the ability to combine with other immuno-oncology therapies that target T-cell activation, such as CTLA-4 and PD-1 antibodies.
[storage]

-20°C
1345810-21-0 suppliers list
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