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ChemicalBook--->CAS DataBase List--->134379-77-4

134379-77-4

134379-77-4 Structure

134379-77-4 Structure
IdentificationBack Directory
[Name]

Dexelvucitabine
[CAS]

134379-77-4
[Synonyms]

RVT
YZ 817
D-D-4FC
DPC-817
Reverset
INCB 8721
RA 131423
beta-D-D-4FC
Dexelvucitabine
2',3'-dideoxy-2',3'-didehydro-5-fluorocytidine
Cytidine,2',3'-didehydro-2',3'-dideoxy-5-fluoro-
5-Fluoro-1-(2',3'-dideoxy-2',3'-didehydro-b-D-arabinofuranosyl)-cytosine
4-AMINO-5-FLUORO-1-[(2R,5S)-5-(HYDROXYMETHYL)-2,5-DIHYDROFURAN-2-YL]PYRIMIDIN-2(1H)-ONE
2’,3’-Dideoxy-2’,3’-didehydro-5-fluoro-cytidine, FddddC, Dexelvucitabine (DFC), Reverset
5-Fluoro-1-(2’,3’-dideoxy-2’,3’-didehydro-β-D-arabinofuranosyl)-cytosine (Dexelvucitabine)
Inhibitor,thymidine,Human immunodeficiency virus,d-d4FC,cytidine,M184V mutation,antiretroviral,inhibit,Reverset,2′-deoxycytidine,viral polymerase,Dexelvucitabine,HIV,resistant viruse,nucleoside reverse transcriptase,HIV-1,Reverse Transcriptase
[Molecular Formula]

C9H10FN3O3
[MDL Number]

MFCD09954118
[MOL File]

134379-77-4.mol
[Molecular Weight]

227.19
Chemical PropertiesBack Directory
[Boiling point ]

394.9±52.0 °C(Predicted)
[density ]

1.66±0.1 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO:0.0(Max Conc. mg/mL);0.0(Max Conc. mM)
[form ]

Solid
[pka]

14.28±0.10(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

Dexelvucitabine is a nucleoside reverse transcriptase inhibitor (NRTI) which had the potential to inhibit HIV-1 replication. The drug was discontinued due to evidence that it causes damage to the pancreas.
[Uses]

Treatment of HIV-1 and HIV-2 infection.
[Brand name]

Reverset (Incyte).
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