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ChemicalBook--->CAS DataBase List--->134362-79-1

134362-79-1

134362-79-1 Structure

134362-79-1 Structure
IdentificationBack Directory
[Name]

RO 0437626
[CAS]

134362-79-1
[Synonyms]

RO 0437626
N-[(1R)-2-[[(1S,2R,3S)-1-(Cyclohexylmethyl)-3-cyclopropyl-2,3-dihydroxypropyl]amino]-2-oxo-1-(4-thiazolylmethyl)ethyl]-1H-benzimidazole-2-carboxamide
1H-Benzimidazole-2-carboxamide, N-[(1R)-2-[[(1S,2R,3S)-1-(cyclohexylmethyl)-3-cyclopropyl-2,3-dihydroxypropyl]amino]-2-oxo-1-(4-thiazolylmethyl)ethyl]-
[Molecular Formula]

C27H35N5O4S
[MDL Number]

MFCD07363878
[MOL File]

134362-79-1.mol
[Molecular Weight]

525.66
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

Soluble to 100 mM in DMSO and to 100 mM in ethanol
[form ]

Powder
Hazard InformationBack Directory
[Uses]

Ro 0437626 is a P2X1 purinergic receptor antagonist.
[Biological Activity]

Selective P2X 1 purinergic receptor antagonist (IC 50 = 3 μ M) that displays > 30-fold selectivity over P2X 2 , P2X 3 and P2X 2/3 receptors (IC 50 > 100 μ M).
[storage]

Store at -20°C
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