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ChemicalBook--->CAS DataBase List--->133841-08-4

133841-08-4

133841-08-4 Structure

133841-08-4 Structure
IdentificationBack Directory
[Name]

7-METHOXY-3-INDAZOLECARBOXYLIC ACID
[CAS]

133841-08-4
[Synonyms]

7-METHOXY-3-INDAZOLECARBOXYLIC ACID
7-METHOXYINDAZOLE-3-CARBOXYLIC ACID
7-METHOXY-1H-INDAZOLE-3-CARBOXYLIC ACID
1H-Indazole-3-carboxylic acid, 7-methoxy-
[Molecular Formula]

C9H8N2O3
[MDL Number]

MFCD05663994
[MOL File]

133841-08-4.mol
[Molecular Weight]

192.17
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Uses]

7-Methoxy-1H-indazole-3-carboxylic Acid is an intermediate in the synthesis of 7-Hydroxy Granisetron (H942675), a metabolite of Granisetron (G780000), a specific serotonin (5HT3) receptor antagonist. Used as an antiemetic. Granisetron HCl is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy. Its main effect is to reduce the activity of the vagus nerve. It does not have much effect on vomiting due to motion sickness. This drug does not have any effect on dopamine receptors or muscarinic receptor.
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