| Identification | Back Directory | [Name]
CIS-(+/-)-1-(AMINOMETHYL)-3,4-DIHYDRO-3-PHENYL-1H-2-BENZOPYRAN-5,6-DIOL HYDROCHLORIDE | [CAS]
130465-39-3 | [Synonyms]
A 68930
A68930HCl
A 68930 hydrochlorid
A 68930 HYDROCHLORIDE
A-68930 hydrochloride
(A68930)
cis-1-(AMinoMethyl)-3-phenylisochroMan-5,6-diol hydrochloride
(1R,3S)-1-(AMinoMethyl)-3-phenylisochroMan-5,6-diol hydrochloride
(1R,3S)-1-(aminomethyl)-3,4-dihydro-5,6-dihydroxy-3-phenyl-1H-2-benzopyran
1-(aminomethyl)-3,4-dihydro-3-phenyl-1H-2-Benzopyran-5,6-diol hydrochloride
cis-(±)-1-Aminoethyl-3,4-dihydro-3-phenyl-1H-2-benzopyran-5,6-diol hydrochloride
CIS-(+/-)-1-(AMINOMETHYL)-3,4-DIHYDRO-3-PHENYL-1H-2-BENZOPYRAN-5,6-DIOL HYDROCHLORIDE | [Molecular Formula]
C16H18ClNO3 | [MDL Number]
MFCD05863727 | [MOL File]
130465-39-3.mol | [Molecular Weight]
307.77 |
| Hazard Information | Back Directory | [Uses]
A 68930 Hydrochloride is a potent and selective agonist at the D1-like dopamine receptor. It demontrated neuroprotective and anti-stress effects in rat model (1,2). | [Biological Activity]
Potent and selective D 1 -like dopamine receptor agonist (EC 50 values are 2.1 and 3910 nM for D 1 -like and D 2 -like receptors respectively). Centrally active following systemic administration in vivo . | [storage]
Store at -20°C | [References]
[1]. kebabian jw, briggs c, britton dr, et al. a68930: a potent and specific agonist for the d-1 dopamine receptor. am j hypertens, 1990, 3(6 pt 2): 40s-42s.
[2]. salmi p. independent roles of dopamine d1 and d2/3 receptors in rat thermoregulation. brain res, 1998, 781(1-2): 188-193.
[3]. deveney am, waddington jl. psychopharmacological distinction between novel full-efficacy "d1-like" dopamine receptor agonists. pharmacol biochem behav, 1997, 58(2): 551-558.
[4]. rasheed n, ahmad a, al-sheeha m, et al. neuroprotective and anti-stress effect of a68930 in acute and chronic unpredictable stress model in rats. neurosci lett, 2011, 504(2): 151-155. |
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Energy Chemical
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