| Identification | Back Directory | [Name]
5ALPHA-CHOLESTAN-3BETA,5ALPHA-DIOL-6-ONE | [CAS]
13027-33-3 | [Synonyms]
YS-64
yakkasterone
CHOLESTANE-6-OXO-3,5-DIOL
5α-hydroxy-6-keto Cholesterol
5α-Hydroxy-6-keto cholesterol
3β,5-Dihydroxy-5α-cholestan-6-one
5ALPHA-HYDROXY-6-KETO CHOLESTEROL
CHOLESTANE-6-OXO-3BETA,5ALPHA-DIOL
CHOLESTAN-3-BETA, 5-ALPHA-DIOL-6-ONE
5ALPHA-CHOLESTAN-3BETA,5ALPHA-DIOL-6-ONE
Cholestan-6-one, 3,5-dihydroxy-, (3β,5α)-
(3S,5R,8S,9S,10R,13R,14S,17R)-3,5-Dihydroxy-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)tetradecahydro-1H-cyclopenta[a]phenanthren-6(10H)-one | [Molecular Formula]
C27H46O3 | [MDL Number]
MFCD00271438 | [MOL File]
13027-33-3.mol | [Molecular Weight]
418.65 |
| Chemical Properties | Back Directory | [Melting point ]
234 °C | [Boiling point ]
528.9±45.0 °C(Predicted) | [density ]
1.061±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 20 mg/ml; DMSO: 0.5 mg/ml; Ethanol: 5 mg/ml | [form ]
A crystalline solid | [pka]
12?+-.0.70(Predicted) |
| Hazard Information | Back Directory | [Uses]
5α-Hydroxy-6-keto Cholesterol Hydrochloride is a major metabolite of cholesterol. | [Definition]
ChEBI: Cholestan-6-oxo-3,5-diol is a cholestanoid. | [Biological Activity]
6-keto-5α-hydroxycholesterol favors tumor progression. cholestan-6-oxo-3β,5α-diolelicits cytotoxicity towards human bronchial 16-HBE cells and plays a key role in mediating cell necrosis post ozone exposure. It is an oncometabolitewhich promotes breast cancer progression and also blocks chemotaxis mediated by polymorphonuclear leukocytes. |
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| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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