| Identification | Back Directory | [Name]
IKK epsilon-IN-1 | [CAS]
1292310-49-6 | [Synonyms]
CS-1801
IKKE-IN-1
IKKε-IN-1
TBK1-IN-1
TBK1/IKKε-IN-2
IKK epsilon-IN-1
TBK1/IKKε inhibitor 2
MDK10496 (IKK epsilon-IN-1)
IKK(epsilon)-IN-1 (IKKE-IN-1)
5-[2-(4-Morpholin-4-ylanilino)pyrimidin-4-yl]-2-(oxan-4-yloxy)benzonitrile
5-(2-((4-Morpholinophenyl)Amino)Pyrimidin-4-Yl)-2-((Tetrahydro-2H-Pyran-4-Yl)Oxy)Benzonitrile
5-[2-[[4-(4-Morpholinyl)phenyl]amino]-4-pyrimidinyl]-2-[(tetrahydro-2H-pyran-4-yl)oxy]benzonitrile
Benzonitrile, 5-[2-[[4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]-2-[(tetrahydro-2H-pyran-4-yl)oxy]-
5-(2-((4-morpholinophenyl)amino)pyrimidin-4-yl)-2-((tetrahydro-2H-pyran-4-yl)oxy)benzonitrile IKKε-IN-1 | [Molecular Formula]
C26H27N5O3 | [MDL Number]
MFCD28167836 | [MOL File]
1292310-49-6.mol | [Molecular Weight]
457.52 |
| Chemical Properties | Back Directory | [Boiling point ]
727.2±70.0 °C(Predicted) | [density ]
1.32±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 21.5 mg/mL (46.99 mM; Need ultrasonic and warming) | [form ]
Powder | [pka]
5.25±0.40(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
TBK1/IKKε-IN-2 is a dual inhibitor of TBK1 and IKKε. | [IC 50]
TBK1: 0.6 nM (IC50, at 5 μM ATP); IKKε: 3.9 nM (IC50, at 10 μM ATP) |
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