Identification | Back Directory | [Name]
(+/-)5(6)-EPOXY-8Z,11Z,14Z,17Z-EICOSATETRAENOIC ACID, METHYL ESTER | [CAS]
127716-49-8 | [Synonyms]
5(6)-EPETE METHYL ESTER BDSCYYACNUKQLZ-AECQIINDSA-N 5,6-EPOXY EICOSATETRAENOIC ACID METHYL ESTER (+/-)5(6)-EPOXY-8Z,11Z,14Z,17Z-EICOSATETRAENOIC ACID, METHYL ESTER (+/-)5(6)-EPOXY-8Z,11Z,14Z,17Z-EICOSATETRAENOIC ACID, METHYL ESTER 2-Oxiranebutanoic acid, 3-(2Z,5Z,8Z,11Z)-2,5,8,11-tetradecatetraen-1-yl-, methyl ester, (2R,3S)-rel- | [Molecular Formula]
C21H32O3 | [MDL Number]
MFCD02259377 | [MOL File]
127716-49-8.mol | [Molecular Weight]
332.48 |
Hazard Information | Back Directory | [Description]
(±)5(6)-EpETE methyl ester is a derivative of 5(6)-EpETE which is stable enough to ship and handle routinely.(±) 5(6)-EpETE methyl ester is a chemically less reactive derivative of 5(6)-EpETE. The active free acid can be generated from the methyl ester by careful base hydrolysis. Epoxy eicosatetraenoic acids (EpETEs) are the epoxygenase metabolites of EPA. A number of vicinal diol metabolites of EpETEs have been detected in the plasma of patients on marine oil dietary supplementation, while in subjects on a typical western diet these compounds are generally not detected.1 The specific biologic activity of 5(6)-EpETE and its methyl ester have not been documented. | [References]
1. Knapp, H.R., Miller, A.J., and Lawson, J.A. Urinary excretion of diols derived from eicosapentaenoic acid during N-3 fatty acid ingestion Prostaglandins 42,47-53(1991). |
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