| Identification | Back Directory | [Name]
Zamifenacinfumarate | [CAS]
127308-98-9 | [Synonyms]
UK-76654 fumarate
Zamifenacinfumarate
(3R)-1-[2-(1-,3-Benzodioxol-5-yl)ethyl]-3-(diphenylmethoxy)piperidinefumarate | [Molecular Formula]
C27H29NO3.C4H4O4 | [MDL Number]
MFCD09263617 | [MOL File]
127308-98-9.mol | [Molecular Weight]
531.602 |
| Chemical Properties | Back Directory | [storage temp. ]
Inert atmosphere,2-8°C | [solubility ]
Soluble to 100 mM in DMSO and to 25 mM in ethanol | [form ]
Powder | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Zamifenacin Fumarate is a selective antagonist of mAChR M3 (M3 muscarinic receptor). | [Biological Activity]
Selective M 3 muscarinic receptor antagonist (pK i values are 8.52, 7.93, 7.90 and 7.78 for M 3 , M 2 , M 1 and M 4 receptors respectively). Displays higher affinity at ileal M 3 receptors (pK i = 9.3) compared to oesophageal and tracheal M 3 receptors (pK i values are 8.8 and 8.2 respectively). In vivo, inhibits gastrointestinal motility in the absence of cardiovascular effects. |
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| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
|