Identification | Back Directory | [Name]
GANGLIOSIDE GD1A DISODIUM SALT | [CAS]
12707-58-3 | [Synonyms]
GD1A GD1A 2NA Ganglioside B1 Ganglioside GII GD1A-GANGLIOSIDE GANGLIOSIDE GD1A disialogangloside GD1a DISIALOGANGLIOSIDE GD1A DISIALOGANGLIOSIDE GDIA GD1a-Ganglioside sodium DISALOGANGLIOSIDE GD1A 2NA DISIALOGANGLIOSIDE GD1A 2NA IV3NEUAC, II3NEUAC-GGOSE4CER Disialoganglioside GD1a ,95% GANGLIOSIDE GD1A DISODIUM SALT Ganglioside GD1a (sodium salt) DISIALOGANGLIOSIDE GD1A, BOVINE Ganglioside GD1a (Porcine Brain) GAL(SA)-GALNAC-GAL(SA)-GLC-CERAMIDE DISIALOGANGLIOSIDE GD1A (NH4+ SALT) Ganglioside GD1a mixture (sodium salt) MONOSIALOGANGLIOSIDE GD1A DISODIUM SALT GANGLIOSIDEGD1ADISODIUMSALT,BOVINEBRAIN GANGLIOSIDE GD1A DISODIUM SALT USP/EP/BP disialoganglioside-gd1A from bovine*brain disialoganglioside G(D1A) from bovine brain ganglioside gd1a, disialo from bovine brain DISIALOGANGLIOSIDE-GD1A CELL CULTURE*TES TED Ganglioside GD1a Mixture (bovine) (ammonium salt) Ganglioside GD1a Mixture (porcine) (ammonium salt) GANGLIOSIDEGD1ADISODIUMSALT,BOVINEBRAIN,CELLCULTUREGRADE Disialoganglioside GD1a from bovine brain,Ganglioside GD1a, disialo from bovine brain | [Molecular Formula]
C84H146N4Na2O39 | [MDL Number]
MFCD00130960 | [MOL File]
12707-58-3.mol | [Molecular Weight]
1882.04 |
Hazard Information | Back Directory | [Description]
Ganglioside GD1a is a sialic acid-containing glycosphingolipid found in brain, erythrocytes, bone marrow, testis, spleen, and liver. It can be shed from the surface of tumor cells into the microenvironment where it influences tumor-host cell interactions to promote tumor cell proliferation, invasion, and metastasis. Ganglioside GD1a (20 μM) also increases endothelial cell proliferation. Furthermore, ganglioside GD1a has been shown to act as a functional coreceptor for toll-like receptor 2 (TLR2), enabling the recruitment of TLR2 to lipid rafts when bound by a bacterial toxin. Ganglioside GD1a mixture contains ganglioside GD1a molecular species with C18:1 and C20:1 sphingoid backbones. | [Chemical Properties]
White powder | [Uses]
Ganglioside GD1a Disodium Salt is an agent with a stimulatory effect on phagocytosis and phagosome-lysosome. | [General Description]
Ganglioside GD1a is an anionic brain ganglioside. It is localized in the inner and outer membrane of nuclear envelope of the neuronal cells. GD1a contains a neutral tetrasaccharide core, with one or two sialic acid on the internal galactose. It also has an additional sialic acid on the non-reducing terminal of galactose. | [storage]
Store at -20°C |
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