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ChemicalBook--->CAS DataBase List--->1260247-42-4

1260247-42-4

1260247-42-4 Structure

1260247-42-4 Structure
IdentificationBack Directory
[Name]

LLL12
[CAS]

1260247-42-4
[Synonyms]

LLL12
LLL-12 (LLL12
5-hydroxy-9,10-dioxo-9,10-dihydroanthracene-1-sulfonamide
[Molecular Formula]

C14H9NO5S
[MOL File]

1260247-42-4.mol
[Molecular Weight]

303.29
Chemical PropertiesBack Directory
[Melting point ]

179-181 °C
[Boiling point ]

618.2±65.0 °C(Predicted)
[density ]

1.626±0.06 g/cm3(Predicted)
[form ]

Solid
[pka]

6.46±0.20(Predicted)
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Description]

LLL12 is a potent STAT3 inhibitor. LLL12 inhibits colony formation and cell migration and works synergistically with doxorubicin and gemcitabine. LLL12 demonstrated a potent inhibitory activity on breast and glioblastoma tumor growth in a mouse xenograft model. LLL12 may be a potential therapeutic agent for human cancer cells expressing constitutive STAT3 signaling.
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