| Chemical Properties | Back Directory | [Melting point ]
184-187 °C(Solv: ethyl acetate (141-78-6)) | [Boiling point ]
416.1±45.0 °C(Predicted) | [density ]
1.071±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 15 mg/ml; DMSO: 25 mg/ml; Ethanol: 5 mg/ml | [form ]
A crystalline solid | [pka]
10.99±0.20(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
2-nonyl-3-hydroxy-4-Quinolone is a bacterial quorum-sensing signal molecule produced by P. aeruginosa.1 It activates a biosensor for the P. aeruginosa gene pqsA, which encodes the first enzyme in the P. aeruginosa biosynthesis of the bacterial quorum-sensing signal molecule 2-heptyl-3-hydroxy-4-quinolone , in a concentration-dependent manner.2 | [References]
1. Nguyen, A.T., Jones, J.W., Ruge, M.A., et al. Iron depletion enhances production of antimicrobials by Pseudomonas aeruginosa J. Bacteriol. 197(14),2265-2275(2015).
2. Fletcher, M.P., Diggle, S.P., Crusz, S.A., et al. A dual biosensor for 2-alkyl-4-quinolone quorum-sensing signal molecules Environ. Microbiol. 9(11),2683-2693(2007). |
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