| Identification | Back Directory | [Name]
N-(1-(3,4-Dihydroxyphenyl)propan-2-yl)oleamide | [CAS]
1258011-97-0 | [Synonyms]
N-(1-(3,4-Dihydroxyphenyl)propan-2-yl)oleamide | [Molecular Formula]
C27H45NO3 | [MOL File]
1258011-97-0.mol | [Molecular Weight]
431.65 |
| Hazard Information | Back Directory | [Description]
N-(1-(3,4-Dihydroxyphenyl)propan-2-yl)oleamide binds to the cannabinoid 1 (CB1) receptor with a Ki value of 365 nM in a radioligand binding assay using rat brain homogenate.1 It has an EC50 value of 698 nM for the peroxisome proliferator-activated receptor α (PPARα) in a luciferase reporter assay and, in rats, it decreases food intake. It does not inhibit fatty acid amide hydrolase (FAAH). | [References]
1. Almeida, B., Joglar, J., Rojas, M.J.L., et al. Synthesis of fatty acid amides of catechol metabolites that exhibit antiobesity properties. ChemMedChem 4;5(10),1781-1787(2010). |
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