| Identification | Back Directory | [Name]
LAVENDUSTIN C | [CAS]
125697-93-0 | [Synonyms]
HDBA
COMPOUND 5
NSC 666251
LAVENDUSTIN C
5-(2,5-DIHYDROXYBENZYLAMINO)SALICYLIC ACID
5-(N-2,5-DIHYDROXYBENZYL)AMINOSALICYLIC ACID
5-(N-2',5'-DIHYDROXYBENZYL)AMINOSALICYLIC ACID
N-(2',5'-DIHYDROXYBENZYL)-5-AMINOSALICYLIC ACID
2-hydroxy-5-(2,5-dihydrobenzyl)aminobenzoic acid
2-HYDROXY-5-(2,5-DIHYDROXYBENZYLAMINO)BENZOIC ACID
5-(2,5-DIHYDROXYBENZYLAMINO)-2-HYDROXYBENZOIC ACID
[2-HYDROXY-5-[N-(2',5'-DIHYDROXYBENZYL)AMINO]BENZOIC ACID
5-[(2,5-dihydroxyphenyl)methylamino]-2-hydroxybenzoic acid
5-[(2,5-dihydroxyphenyl)methylamino]-2-hydroxy-benzoic acid
5-(2,5-Dihydroxybenzylamino)salicylic acid, N-(2,5-Dihydroxybenzyl)-5-aminosalicylic acid
Compound 5, HDBA, N-(2μ,5μ-Dihydroxybenzyl)-5-aminosalicylic acid, [2-Hydroxy-5-[N-(2μ,5μ-dihydroxybenzyl)amino]benzoic acid | [Molecular Formula]
C14H13NO5 | [MDL Number]
MFCD00153955 | [MOL File]
125697-93-0.mol | [Molecular Weight]
275.26 |
| Chemical Properties | Back Directory | [Appearance]
Brown Solid | [Melting point ]
193-195°C dec. | [Boiling point ]
597.5±50.0 °C(Predicted) | [density ]
1.551±0.06 g/cm3(Predicted) | [storage temp. ]
−20°C
| [solubility ]
DMSO: soluble
| [form ]
solid
| [pka]
2.32±0.10(Predicted) | [color ]
Light Beige to Brown | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Chemical Properties]
Brown Solid | [Uses]
Shows potent tyrosine kinase inhibitory activity | [Description]
Lavendustin C, a derivative of a Streptomyces griseolavendus butyl acetate extract, is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase with an IC50 value of 0.012 μM. Lavendustin C also inhibits pp60c-src(+) kinase and Ca2+ calmodulin-dependent kinase II with IC50 values of 0.5 and 0.2 μM, respectively. At a concentration of 10-150 μM, lavendustin C inhibits tyrosine kinase-associated neutrophil degranulation and superoxide generation. | [Definition]
ChEBI: 5-[(2,5-dihydroxyphenyl)methylamino]-2-hydroxybenzoic acid is an aromatic amine. |
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| Company Name: |
Twochem Co.Ltd.
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021-58111628 15800915896 |
| Website: |
cn.twochem.com |
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