| Identification | Back Directory | [Name]
Dibenzocyclooctyne-aMine | [CAS]
1255942-06-3 | [Synonyms]
DBCO-NH2
DBCO-amine
DBCO-(CH2)2-NH2
ADIBO-CH2CH2NH2·TFA
DBCO-(CH2)2-NH2.TFA
DBCO-(CH2)3-NH2.TFA
Dibenzocyclooctyne-amine
DBCO-Amine
(DBCO amine)
Azadibenzocylooctyne-amine
Azadibenzocyclooctyne-amine
Azadibenzocyclooctyne-(CH2)2-amine TFA
Dibenzocyclooctyne-aMine for Copper-free Click CheMistry
Dibenzocyclooctyne-amine (This product is unavailable in the U.S.)
1-Propanone, 3-amino-1-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-
3-amino-1-{2-azatricyclo[10.4.0.0?,?]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl}propan-1-one | [Molecular Formula]
C18H16N2O | [MDL Number]
MFCD22380759 | [MOL File]
1255942-06-3.mol | [Molecular Weight]
276.33 |
| Chemical Properties | Back Directory | [Melting point ]
86-96°C | [Boiling point ]
549.9±50.0 °C(Predicted) | [density ]
1.25±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C | [form ]
Solid | [pka]
8.81±0.10(Predicted) | [color ]
Yellow to Orange | [InChI]
InChI=1S/C18H16N2O/c19-12-11-18(21)20-13-16-7-2-1-5-14(16)9-10-15-6-3-4-8-17(15)20/h1-8H,11-13,19H2 | [InChIKey]
PQFQVUMDOWUGMK-CHMOPDDRSA-N | [SMILES]
C(N1CC2=CC=CC=C2C#CC2=CC=CC=C12)(=O)CCN |
| Hazard Information | Back Directory | [Description]
DBCO-amine is a simple building block containing a DBCO moiety and will add minimal spacer to the modified molecules. In the presence of activators such as EDC or HATU, this reagent can be used to derivatize carboxyl groups or activated esters (e.g. The NHS ester) through a stable amide bond. DBCO is commonly used for copper-free Click Chemistry reactions. | [Uses]
Azadibenzocyclooctyne amine is a carbonyl reactive reagent used to incorporate ADIBO into organic compounds, surfaces or particlesAzadibenzocyclooctyne amine is widely useful in strain-promoted copper-free azide-alkyne cycloaddition reactions. It reacts with azide functionalized compounds or bimolecules to give stable triazole linkage without a need for a Cu(I) catalyst. |
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