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ChemicalBook--->CAS DataBase List--->125546-04-5

125546-04-5

125546-04-5 Structure

125546-04-5 Structure
IdentificationBack Directory
[Name]

(2R,4S)-4-(2H-tetrazol-5-ylmethyl)piperidine-2-carboxylic acid
[Synonyms]

LY 233053
FAAVTENFCLADRE-RITPCOANSA-N
(2R,4S)-4-(2H-tetrazol-5-ylmethyl)piperidine-2-carboxylic acid
(2R*,4S*)-4-(1H-Tetrazol-5-ylmethyl)-2-piperidinecarboxylicacid
2-Piperidinecarboxylic acid, 4-(2H-tetrazol-5-ylmethyl)-, (2R,4S)-rel-
[Molecular Weight]

211.22
Hazard InformationBack Directory
[Biological Activity]

Competitive NMDA receptor antagonist (IC 50 = 7 nM) that displays no affinity for AMPA or kainate receptors at a concentration of 10 μ M. Inhibits NMDA-induced neuronal degeneration and protects from NMDA-induced convulsions in neonatal rats.
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