| Identification | Back Directory | [Name]
Termitomycamide B | [CAS]
1254277-89-8 | [Synonyms]
Termitomycamide B
(9Z,12Z)-N-[2-(1H-indol-2-yl)-2-oxoethyl]octadeca-9,12-dienamide | [Molecular Formula]
C28H40N2O2 | [MOL File]
1254277-89-8.mol | [Molecular Weight]
436.63 |
| Hazard Information | Back Directory | [Description]
Endoplasmic reticulum (ER) stress, caused by accumulation of misfolded proteins and a disruption of calcium homeostasis, has been linked to several neuronal diseases including, Parkinson’s, Alzheimer’s, and prion diseases. A screen for protective activity against ER stress-dependent cell death identified termitomycamides, extracts from the fruiting bodies of T. titanicus, a notably large edible mushroom that is cultivated symbiotically in the nests of termites Termitomycamide B is a fatty acid isolated from T. titanicus that at a dose of 0.1 μg/ml protects against ER stress-dependent cell death in Neuro2a cells induced by tunicamycin. |
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Resenbio
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029-86354885 |
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www.xarxbio.com |
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