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ChemicalBook--->CAS DataBase List--->1245792-51-1

1245792-51-1

1245792-51-1 Structure

1245792-51-1 Structure
IdentificationBack Directory
[Name]

BCI
[CAS]

1245792-51-1
[Synonyms]

BCI
(E)-BCI
BCI - NSC 150117
1H-Inden-1-one, 3-(cyclohexylamino)-2,3-dihydro-2-(phenylmethylene)-, (2E)-
[Molecular Formula]

C22H23NO
[MOL File]

1245792-51-1.mol
[Molecular Weight]

317.42
Questions And AnswerBack Directory
[Description]

BCI ((E)-BCI, compound 1) is an allosteric dual specificity phosphatase (DUSP) inhibitor with EC50 of 13.3 μM and 8.0 μM in cells for DUSP6 and DUSP1, respectively.
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMSO:125.0(Max Conc. mg/mL);393.79(Max Conc. mM)
[form ]

Solid
[color ]

Off-white to yellow
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501
Hazard InformationBack Directory
[Definition]

ChEBI: (2E)-2-benzylidene-3-(cyclohexylamino)indan-1-one is a 2-benzylidene-3-(cyclohexylamino)indan-1-one in which the double bond has E configuration. An inhibitor of the dual specificity phosphatase 6 (Dusp6). It has a role as an EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor and an apoptosis inducer.
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