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ChemicalBook--->CAS DataBase List--->1245606-71-6

1245606-71-6

1245606-71-6 Structure

1245606-71-6 Structure
IdentificationBack Directory
[Name]

1H-Pyrrole-2,5-dione, 1-[4-[2-(4-Methylphenyl)-1,2-diphenylethenyl]phenyl]-
[CAS]

1245606-71-6
[Synonyms]

TPE-MI
TPE-Thiol
1-{4-[1,2-Diphenyl-2-(p-tolyl)vinyl]phenyl}-1H-pyrrole-2,5-dione
(E)-1-(4-(1,2-diphenyl-2-p-tolylvinyl)phenyl)-1H-pyrrole-2,5-dione
1H-Pyrrole-2,5-dione, 1-[4-[2-(4-Methylphenyl)-1,2-diphenylethenyl]phenyl]-
[Molecular Formula]

C31H23NO2
[MOL File]

1245606-71-6.mol
[Molecular Weight]

441.52
Chemical PropertiesBack Directory
[form ]

solid
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Uses]

TPE-Thiol is an aggregation-induced emission (AIE) material for the "Click" chemistry, with alkene and thio group detection.
[General Description]

Aggregation-induced emission luminogens (AIEgen) were tailored to detect biological thiols. Maleimide is attached to the TPE core, giving TPE-Thiol.16. The reaction is inspired by the fast and efficient thiolene click reaction between maleimide and thiols, TPE-Thiol is not emissive in both solution and aggregated states, due to the photo-induced electron transfer from TPE to maleimide. However, reaction with thiol groups can interrupt the electron transfer process and turn-on the emission of TPE. TPE-Thiol can be used for labelling of protein carrying cysteine residues in the physiological media and poly(acrylamide) gel electrophoresis assays.
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