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ChemicalBook--->CAS DataBase List--->1242137-18-3

1242137-18-3

1242137-18-3 Structure

1242137-18-3 Structure
IdentificationBack Directory
[Name]

Oxo Enzalutamide
[CAS]

1242137-18-3
[Synonyms]

Oxo Enzalutamide
4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-2,4-dioxo-1-imidazolidinyl]-2-fluoro-N-methylbenzamide
Benzamide, 4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-2,4-dioxo-1-imidazolidinyl]-2-fluoro-N-methyl-
[Molecular Formula]

C21H16F4N4O3
[MDL Number]

MFCD34471735
[MOL File]

1242137-18-3.mol
[Molecular Weight]

448.37
Chemical PropertiesBack Directory
[density ]

1.48±0.1 g/cm3(Predicted)
[pka]

13.99±0.46(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]


GHS08,GHS07
[Signal word ]

Danger
[Hazard statements ]

H360-H302
[Precautionary statements ]

P264-P270-P301+P312-P330-P501
Hazard InformationBack Directory
[Uses]

Oxo-MDV 3100 (Oxo-enzalutamide) is an impurity of Enzalutamide (M199800), which is an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex. Enzalutamide has been shown to induce tumor cell apoptosis, and is used for the treatment of castration-resistant prostate cancer.
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