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ChemicalBook--->CAS DataBase List--->1240494-13-6

1240494-13-6

1240494-13-6 Structure

1240494-13-6 Structure
IdentificationBack Directory
[Name]

VZRIHFZJVIOJBE-UHFFFAOYSA-N
[CAS]

1240494-13-6
[Synonyms]

VZRIHFZJVIOJBE-UHFFFAOYSA-N
[Molecular Formula]

C19H16BFN2O3S
[MDL Number]

MFCD28963933
[MOL File]

1240494-13-6.mol
[Molecular Weight]

382.22
Chemical PropertiesBack Directory
[density ]

1.39±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

8.45±0.53(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Description]

SX-517 is a potent noncompetitive boronic acid CXCR1/2 antagonist. SX-517 inhibited CXCL1-induced Ca(2+) flux (IC50 = 38 nM) in human PMNs but had no effect on the Ca(2+) flux induced by C5a, fMLF, or PAF. SX-517 is the first reported boronic acid chemokine antagonist and represents a novel pharmacophore for CXCR1/2 antagonism.
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