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IdentificationBack Directory
[MDL Number]

MFCD16620390
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[solubility ]

DMF: 3 mg/ml,DMSO: 2 mg/ml,Ethanol: Slightly soluble,PBS (pH 7.2): 0.2 mg/ml
[form ]

A solid
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501
Hazard InformationBack Directory
[Uses]

DGAT-1 inhibitor 3 (compound 10) is a potent DGAT-1 inhibitor with an IC50 value of 0.038 μM. DGAT-1 inhibitor 3 has the potential for the research of obesity and diabetes[1].
[storage]

-20°C
[References]

[1] Qian Y, et al. Discovery of orally active carboxylic acid derivatives of 2-phenyl-5-trifluoromethyloxazole-4-carboxamide as potent diacylglycerol acyltransferase-1 inhibitors for the potential treatment of obesity and diabetes. J Med Chem. 2011 Apr 14;54(7):2433-46. DOI:10.1021/jm101580m
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