| Identification | Back Directory | [Name]
Proline, 1-acetyl-2-[[4-(Methylsulfonyl)phenyl]Methyl]-, phenylMethyl ester | [CAS]
1228439-36-8 | [Synonyms]
KCC2 blocker 1
XFXZWVGQXNFWDE-JOCHJYFZSA-N
Proline, 1-acetyl-2-[[4-(Methylsulfonyl)phenyl]Methyl]-, phenylMethyl ester | [Molecular Formula]
C22H25NO5S | [MDL Number]
MFCD25977014 | [MOL File]
1228439-36-8.mol | [Molecular Weight]
415.503 |
| Hazard Information | Back Directory | [Biological Activity]
KCC2 blocker 1 is an orally active and selective K+-Cl- cotransporter KCC2 blocker with an IC50 of 1 μM. KCC2 blocker 1 is a benzyl prolinate and has antiepileptic effect[1]. | [storage]
Store at -20°C | [References]
[1]. Pégurier C, et al. Benzyl prolinate derivatives as novel selective KCC2 blockers. Bioorg Med Chem Lett. 2010 Apr 15;20(8):2542-5. |
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