| Identification | Back Directory | [Name]
H-ALA-SER-ALA-SER-SER-LEU-MET-ASP-LYS-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP-OH | [CAS]
121204-87-3 | [Synonyms]
4 ALA ET-1
[Ala1,3,11,15]ET-1
ASASSLMDKEAVYFAHLDIIW
[ALA1,3,11,15]-ENDOTHELIN
[ALA1,3,11,15]ENDOTHELIN-I
(ALA1,3,11,15)-ENDOTHELIN-1
endothelin 1, Ala(1,3,11,15)-
[ALA1,3,11,15] ENDOTHELIN-1, HUMAN
[ALA1,3,11,16]-ENDOTHELIN 1, HUMAN
ALA-SER-ALA-SER-SER-LEU-MET-ASP-LYS-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP
H-ALA-SER-ALA-SER-SER-LEU-MET-ASP-LYS-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP-OH
H-ALA-SER-ALA-SER-SER-LEU-MET-ASP-LYS-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP-OH USP/EP/BP
ALA-SER-ALA-SER-SER-LEU-MET-ASP-LYS-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP: ASASSLMDKEAVYFAHLDIIW
L-Ala-L-Ser-L-Ala-L-Ser-L-Ser-L-Leu-L-Met-L-Asp-L-Lys-L-Glu-L-Ala-L-Val-L-Tyr-L-Phe-L-Ala-L-His-L-Leu-L-Asp-L-Ile-L-Ile-L-Trp-OH
L-Ala-L-Ser-L-Ala-L-Ser-L-Ser-L-Leu-L-Met-L-αAsp-L-Lys-L-αGlu-L-Ala-L-Val-L-Tyr-L-Phe-L-Ala-L-His-L-Leu-L-αAsp-L-Ile-L-Ile-L-Trp-OH
(Ala1·3·11·15)-Endothelin-1 trifluoroacetate salt H-Ala-Ser-Ala-Ser-Ser-Leu-Met-Asp-Lys-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp-OH trifluoroacetate salt
L-Tryptophan, L-alanyl-L-seryl-L-alanyl-L-seryl-L-seryl-L-leucyl-L-methionyl-L-α-aspartyl-L-lysyl-L-α-glutamyl-L-alanyl-L-valyl-L-tyrosyl-L-phenylalanyl-L-alanyl-L-histidyl-L-leucyl-L-α-aspartyl-L-isoleucyl-L-isoleucyl- | [Molecular Formula]
C109H163N25O32S | [MDL Number]
MFCD00143562 | [MOL File]
121204-87-3.mol | [Molecular Weight]
2367.67 |
| Chemical Properties | Back Directory | [Boiling point ]
2391.5±65.0 °C(Predicted) | [density ]
1.319±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [form ]
Solid | [Water Solubility ]
Soluble to 1 mg/ml in water |
| Hazard Information | Back Directory | [Uses]
[Ala1,3,11,15]-Endothelin 1 may be used to assess the effects of endothelin-1 and [Ala1,3,11,15]-endothelin 1 produced by ETA and ETB receptors, in the presence of BQ-123, in anaesthetized rat. | [General Description]
[Ala1,3,11,15]-Endothelin 1 is a linear endothelin (ET)-1 analogue, and acts as an ETB receptor agonist. ET-1 is a peptide that acts as both, a vasodilator and a vasoconstrictor. It is a ligand for ET receptor, which is of two types, ETA and ETB. ETB receptor is found in the vascular endothelial cells of cardiovascular tissues. | [Biochem/physiol Actions]
Selective agonist for ETB endothelin receptors. | [storage]
Desiccate at -20°C |
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