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ChemicalBook--->CAS DataBase List--->1211565-08-0

1211565-08-0

1211565-08-0 Structure

1211565-08-0 Structure
IdentificationBack Directory
[Name]

N-[(1R,2R)-2-(1-Piperidinyl)cyclohexyl]-N′-[4-(trifluoroMethyl)phenyl]squaraMide
[CAS]

1211565-08-0
[Synonyms]

Rawal Squaramide Organocatalyst
N-[(1R,2R)-2-(1-Piperidinyl)cyclohexyl]-N′-[4-(trifluoroMethyl)phenyl]squaraMide
N-[(1R,2R)-2-(1-Piperidinyl)cyclohexyl]-N'-[4-(trifluoromethyl)phenyl]squaramide 95%
3-[[(1R,2R)-2-(1-piperidinyl)cyclohexyl]aMino]-4-[[4-(trifluoroMethyl)phenyl]aMino]-3-Cyclobutene-1,2-dione
3-(((1R,2R)-2-(Piperidin-1-yl)cyclohexyl)amino)-4-((4-(trifluoromethyl)phenyl)amino)cyclobut-3-ene-1,2-dione
3-Cyclobutene-1,2-dione, 3-[[(1R,2R)-2-(1-piperidinyl)cyclohexyl]amino]-4-[[4-(trifluoromethyl)phenyl]amino]-
3-[[(1R,2R)-2-(1-Piperidinyl)cyclohexyl]amino]-4-[[4- (trifluoromethyl)phenyl]amino]-3-cyclobutene-1,2-dione,99%e.e.
3-[[(1R,2R)-2-(1-Piperidinyl)cyclohexyl]amino]-4-[[4-(trifluoromethyl)phenyl]amino]-3-cyclobutene-1,2-dione, 98%, (99% ee)
[Molecular Formula]

C22H26F3N3O2
[MDL Number]

MFCD18827464
[MOL File]

1211565-08-0.mol
[Molecular Weight]

421.46
Chemical PropertiesBack Directory
[Melting point ]

250 °C (decomp)
[Boiling point ]

497.4±55.0 °C(Predicted)
[density ]

1.31±0.1 g/cm3(Predicted)
[pka]

8.97±0.20(Predicted)
[optical activity]

[α]/D -42.0±2.0°, c = 1 in DMSO
Safety DataBack Directory
[Symbol(GHS) ]


GHS05,GHS07
[Signal word ]

Danger
[Hazard statements ]

H315-H318-H335
[Precautionary statements ]

P280-P302+P352-P305+P351+P338+P310
[Hazard Codes ]

C
[Risk Statements ]

37/38-41
[Safety Statements ]

26-39
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

It can act as a catalyst for the asymmetric tandem aza-Michael addition-protonation between 1-nitro cyclohexene and 4-methoxyaniline to form the corresponding α-arylamino-β-nitro cyclohexane in a 35:65 trans/cis mixture.
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