| Identification | Back Directory | [Name]
6-Fluoro-4-nitro-3H-isobenzofuran-1-one | [CAS]
1207453-90-4 | [Synonyms]
6-Fluoro-4-nitro-3H-isobenzofuran-1-one
6-fluoro-4-nitroisobenzofuran-1(3H)-one | [Molecular Formula]
C8H4FNO4 | [MDL Number]
MFCD22370184 | [MOL File]
1207453-90-4.mol | [Molecular Weight]
197.12 |
| Questions and Answers (Q&A) | Back Directory | [Description]
6-fluoro-4-nitro-3H-isobenzofuran-1-one is a kind of benzofuran
derivative. As a kind of isobenzofuranone, it can be used to enhance
aroma in perfumery. It also has certain pharmacological effects such
as antioxidant activity and antiplatelet activity. | [References]
Boden, Richard M, and W. L. Schreiber. "Use of 1 (3H)- isobenzofuranone in perfumery." US, US 5665697 A. 1997.
Ma, F., et al. "Antiplatelet activity of 3-butyl-6-bromo-1 (3H)- isobenzofuranone on rat platelet aggregation. " Journal of Thrombosis & Thrombolysis 33.1(2012): 64-73.
Pahari, Pallab, B. Senapati, and D. Mal. "Regiospecific Synthesis of Isopestacin, a Naturally Occurring Isobenzofuranone Antioxidant." Cheminform 45.26(2004): 5109-5112.
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| Hazard Information | Back Directory | [Uses]
6-Fluoro-4-nitro-1(3H)-isobenzofuranone appeared as a reactant in the synthesis of a Poly(ADP-ribose) Polymerase-1/2 Inhibitor, which is a proposed anticancer agent. |
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