| Identification | Back Directory | [Name]
Febuxostat Descyano Impurity | [CAS]
1206550-99-3 | [Synonyms]
Febuxostat-5
3-Descyano Febuxostat
Febuxostat Impurity IV
Febuxostat Descyano Impurity
2-(4-isobutoxyphenyl)-4-methylthiazole
2-(4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid
2-[4-(2-methylpropoxy)phenyl]-4-methylthiazole-5-carboxylic Acid
5-Thiazolecarboxylic acid, 4-methyl-2-[4-(2-methylpropoxy)phenyl]-
Febuxostat Impurity 13/Febuxostat Descyano Impurity/2-(4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid | [Molecular Formula]
C15H17NO3S | [MOL File]
1206550-99-3.mol | [Molecular Weight]
291.37 |
| Chemical Properties | Back Directory | [Melting point ]
192-194°C | [Boiling point ]
471.5±55.0 °C(Predicted) | [density ]
1.213±0.06 g/cm3(Predicted) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
1.30±0.37(Predicted) | [color ]
Off-White to Pale Beige |
| Hazard Information | Back Directory | [Uses]
3-Descyano Febuxostat is an impurity of Febuxostat (F229000), a xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout. |
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