| Identification | Back Directory | [Name]
Fluorobexarotene | [CAS]
1190848-23-7 | [Synonyms]
Fluorobexarotene
2-Fluoro-4-[1-(5-,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic acid
Benzoic acid, 2-fluoro-4-[1-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]- | [Molecular Formula]
C24H27FO2 | [MOL File]
1190848-23-7.mol | [Molecular Weight]
366.47 |
| Chemical Properties | Back Directory | [Boiling point ]
484.7±45.0 °C(Predicted) | [density ]
1.082±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
<36.65mg/ml in DMSO; <9.16mg/ml in ethanol | [form ]
Solid | [pka]
3.15±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Fluorobexarotene is a retinoid X receptor (RXR) agonist, which facilitates β-amyloid clearance across blood-brain barrier; RXR activation has the potential to mitigate Aβ brain burden by promoting both the metabolic and BBB clearance of Aβ, offering a novel approach to the treatment of Alzheimer’s disease. | [storage]
Store at -20°C |
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