| Identification | Back Directory | [Name]
AN3199 | [CAS]
1187187-10-5 | [Synonyms]
AN3199
AN 3199;AN-3199
3-Pyridinecarboxylic acid, 6-[(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-, butyl ester | [Molecular Formula]
C17H18BNO5 | [MDL Number]
MFCD29924720 | [MOL File]
1187187-10-5.mol | [Molecular Weight]
327.14 |
| Chemical Properties | Back Directory | [Boiling point ]
468.7±55.0 °C(Predicted) | [density ]
1.27±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 100 mg/mL (305.68 mM) | [form ]
Solid | [pka]
6.91±0.20(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
AN3199 is a PDE4 inhibitor with IC50 of 94.5 nM.IC50 value: 94.5 nM | [References]
[1]. Zhang YK, et al. Design and synthesis of boron-containing PDE4 inhibitors using soft-drug strategy for potential dermatologic anti-inflammatory application. Bioorg Med Chem Lett. 2010 Apr 1;20(7):2270-4. [2]. Akama Tsutomu, et al. Preparation of boron-containing small molecules as anti-inflammatory agents. From PCT Int. Appl. (2009), WO 2009111676 A2 20090911. |
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