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ChemicalBook--->CAS DataBase List--->1179-69-7

1179-69-7

1179-69-7 Structure

1179-69-7 Structure
IdentificationBack Directory
[Name]

THIETHYLPERAZINE MALEATE (200 MG)
[CAS]

1179-69-7
[Synonyms]

gs-95
torecan
tresten
toresten
nsc-130044
torecanmaleate
2-butenedioate
torecanbimaleate
torecandimaleate
(z)-10h-phenothiazin
thiethylperazinemaleate
thiethylperazinedimaleate
THIETHYLPERAZINE MALEATE (200 MG)
thiethylperazine di(hydrogen maleate)
2-(ethylthio)-10-(3-(4-methyl-1-piperazinyl)propyl)-phenothiazindimaleat
2-(ethylthio)-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazinedimaleate
2-(ethylthio)-10-(3-(4-methyl-1-piperazinyl)propyl)-phenothiazinmaleate(1
3-ethylmercapto-10-(1’-methylpiperazinyl-4’-propyl)phenothiazinedimaleate
2-ethylmercapto-10-(3-(1-methyl-4-piperazinyl)propyl)phenothiazinedimaleate
2-(ethylthio)-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazinemaleate(1:2
2-(ethylthio)-10-(3-(4-methyl-1-piperazinyl)propyl)-phenothiazinmaleate(1:2)
[EINECS(EC#)]

214-648-9
[Molecular Formula]

C4H2O4-2
[MDL Number]

MFCD01706868
[MOL File]

1179-69-7.mol
[Molecular Weight]

114.056
Chemical PropertiesBack Directory
[Melting point ]

>146oC (dec.)
[storage temp. ]

Hygroscopic, -20°C Freezer, Under inert atmosphere
[solubility ]

DMSO (Slightly), Methanol (Slightly, Heated)
[form ]

Solid
[color ]

Off-White to Pale Yellow
[Stability:]

Hygroscopic
Safety DataBack Directory
[Symbol(GHS) ]


GHS07,GHS09
[Signal word ]

Warning
[Hazard statements ]

H302-H400-H410
[Precautionary statements ]

P273-P391-P501-P273-P391-P501-P264-P270-P301+P312-P330-P501
[HS Code ]

2934302700
Hazard InformationBack Directory
[Uses]

Thiethylperazine Maleate is used a phenothiazine derivative used in the treatment of multi-drug resistant (MDR) bacterial infections. Antibacterial.
[in vivo]

Thiethylperazine (3 mg/kg; intramuscular injection; twice daily; for 30 days; young APP/PS1 mice) treatment significantly reduces Aβ42 levels in APP/PS1 mice[2].

Animal Model:Young Aβ precursor protein (APPswe) and mutant presenilin-1 (PS1) (APP/PS1) mice[2]
Dosage:3 mg/kg
Administration:Intramuscular injection; twice daily; for 30 days
Result:Significantly reduced Aβ42 levels in APP/PS1 mice.
[IC 50]

D2 Receptor; H1 Receptor
[storage]

4°C, away from moisture and light
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