| Identification | Back Directory | [Name]
MMP-9 INHIBITOR I | [CAS]
1177749-58-4 | [Synonyms]
MMP-9 Inhibitor
MMP-9 INHIBITOR I
MMP-9 Inhibitor II
MMP-9 Inhibitor I - CAS 1177749-58-4 - Calbiochem
Benzamide, 5-[(diethylamino)methyl]-N-hydroxy-2-[[(4-methoxyphenoxy)sulfinyl](phenylmethyl)amino]-3-methyl- | [Molecular Formula]
C27H33N3O5S | [MDL Number]
MFCD22581508 | [MOL File]
1177749-58-4.mol | [Molecular Weight]
511.63 |
| Chemical Properties | Back Directory | [density ]
1.276±0.06 g/cm3(Predicted) | [storage temp. ]
-20C | [solubility ]
DMSO: 10mg/mL | [form ]
Off-white solid | [pka]
8.28±0.42(Predicted) | [color ]
off-white |
| Hazard Information | Back Directory | [Definition]
ChEBI: MMP9 inhibitor I is a hydroxamic acid that is N-hydroxy-3-methylbenzamide in which the the hydrogens at positions 2 and 5 have been replaced by benzyl[(4-methoxyphenyl)sulfonyl]amino and (diethylamino)methyl groups, respectively. It is a cell-permeable, potent, selective, and reversible inhibitor of matrix metallopeptidase-9 (MMP-9, EC 3.4.24.35). It has a role as an EC 3.4.24.35 (gelatinase B) inhibitor. It is a hydroxamic acid, a tertiary amino compound, a sulfonamide and an aromatic ether. | [General Description]
A cell-permeable, potent, selective, and reversible inhibitor of MMP-9 (IC50 = 5 nM). Also inhibits MMP-1 (IC50 = 1.05 μM) and MMP-13 IC50 = 113 nM) at higher concentrations. | [Biochem/physiol Actions]
Primary TargetMMP-9 |
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