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ChemicalBook--->CAS DataBase List--->1176541-11-9

1176541-11-9

1176541-11-9 Structure

1176541-11-9 Structure
IdentificationBack Directory
[Name]

AL 8810 methyl ester
[CAS]

1176541-11-9
[Synonyms]

AL 8810 methyl ester
SUQUNXDCROKALM-ZOXVUOEWSA-N
5-Heptenoic acid, 7-[(1R,2R,3S,5S)-2-[(1E,3R)-3-(2,3-dihydro-1H-inden-2-yl)-3-hydroxy-1-propen-1-yl]-3-fluoro-5-hydroxycyclopentyl]-, methyl ester, (5Z)-
[Molecular Formula]

C25H33FO4
[MOL File]

1176541-11-9.mol
[Molecular Weight]

416.53
Chemical PropertiesBack Directory
[Boiling point ]

554.5±50.0 °C(Predicted)
[density ]

1.17±0.1 g/cm3(Predicted)
[solubility ]

DMF: 30 mg/ml; DMSO: 25 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 0.5 mg/ml
[form ]

A crystalline solid
[pka]

14.21±0.70(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501
Hazard InformationBack Directory
[Description]

AL 8810 is an 11β-fluoro analog of prostaglandin F (PGF) which acts as a potent and selective antagonist at the FP receptor. AL 8810 methyl ester is a lipid soluble, esterified prodrug form of AL 8810 analogous to the commonly used therapeutic intraocular prostaglandin compounds such as latanoprost and travoprost. The pharmacology of AL 8810 methyl ester has not been published.
[Definition]

ChEBI:AL 8810 methyl ester is a member of indanes.
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