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ChemicalBook--->CAS DataBase List--->117091-64-2

117091-64-2

117091-64-2 Structure

117091-64-2 Structure
IdentificationBack Directory
[Name]

Etoposide phosphate
[CAS]

117091-64-2
[Synonyms]

Etopofos
ETOPOPHOS
BMY 40481
ETOPOSIDE PHOSPHATE
ETOPOSIDE PHOSPHONATE
Etoposide 4'-Phosphate
ETOPOSIDEPHOSPHATE,ETOPOPHOS
Etoposide phosphate≥ 98% (HPLC)
ETOPOSIDE PHOSPHONATE, ETOPOPHOS
BMY-40481, Etoposide 4'-Dihydrogenphosphate
(5R,5aR,8aR,9S)-5-[3,5-DiMethoxy-4-(phosphonooxy)phenyl]-9-[[4,6-O-(1R)-ethylidene-β-D-glucopyranosyl]oxy]-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one
[5R-[5α,5aβ,8aα,9β(R*)]]-5-[3,5-DiMethoxy-4-(phosphonooxy)phenyl]-9-[(4,6-O-ethylidene-β-D-glucopyranosyl)oxy]-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one
Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 5-[3,5-dimethoxy-4-(phosphonooxy)phenyl]-9-[[4,6-O-(1R)-ethylidene-b-D-glucopyranosyl]oxy]-5,8,8a,9-tetrahydro-, (5R,5aR,8aR,9S)-
Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 5-[3,5-dimethoxy-4-(phosphonooxy)phenyl]-9-[[4,6-O-(1R)-ethylidene-β-D-glucopyranosyl]oxy]-5,8,8a,9-tetrahydro-, (5R,5aR,8aR,9S)-
[EINECS(EC#)]

630-364-1
[Molecular Formula]

C29H33O16P
[MDL Number]

MFCD00270859
[MOL File]

117091-64-2.mol
[Molecular Weight]

668.54
Chemical PropertiesBack Directory
[Boiling point ]

907.7±75.0 °C(Predicted)
[density ]

1?+-.0.1 g/cm3(Predicted)
[storage temp. ]

-20°C
[form ]

Solid
[pka]

1.13±0.50(Predicted)
[color ]

White to off-white
[Water Solubility ]

Water: 125 mg/mL (186.97 mM)
Safety DataBack Directory
[Symbol(GHS) ]


GHS07,GHS08
[Signal word ]

Danger
[Hazard statements ]

H302-H350-H361d-H412
[Precautionary statements ]

P202-P264-P270-P273-P301+P312-P308+P313
[HS Code ]

2938909090
Hazard InformationBack Directory
[Chemical Properties]

White crystalline powder
[Uses]

As a bioequivalent prodrug of the DNA topoisomerase II inhibitor Etoposide (E933750), Etoposide phosphate can be used in the treatment of a wide variety of hematological malignancies and solid tumors.
[Definition]

ChEBI: Etoposide phosphate is a furonaphthodioxole.
[Brand name]

Etopophos (Bristol-Myers Squibb).
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