| Identification | Back Directory | [Name]
1-Boc-4-amino-4-piperidineacetic acid | [CAS]
1159983-30-8 | [Synonyms]
2-(4-Amino-1-(tert-butoxycarbonyl)
1-Boc-4-amino-4-piperidineacetic acid
2-(1-Boc-4-amino-4-piperidyl)acetic Acid
2-(4-Amino-1-boc-piperidin-4-yl)acetic Acid
2-(4-AMINO-1-(TERT-BUTOXYCARBONYL)PIPERIDIN-4-YL)ACETIC ACID
4-Piperidineacetic acid, 4-amino-1-[(1,1-dimethylethoxy)carbonyl]-
2-[4-amino-1-[(2-methylpropan-2-yl)oxycarbonyl]piperidin-4-yl]acetic acid | [Molecular Formula]
C12H22N2O4 | [MDL Number]
MFCD08460439 | [MOL File]
1159983-30-8.mol | [Molecular Weight]
258.31 |
| Chemical Properties | Back Directory | [Boiling point ]
398.9±27.0 °C(Predicted) | [density ]
1.158±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C(protect from light) | [pka]
4.66±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
1-Boc-4-amino-4-piperidineacetic acid can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process. | [Synthesis]
A mixture of 4-oxo-piperidine- 1 -carboxylic acid tert-butyl ester (3.5 g, 17.55 mmol) (Sigma- Aldrich), malonic acid (2.0 g, 19.30 mmol) and ammonium acetate (3.1 g, 40.36 mmol) in n-BuOH was refluxed for 3 h. After cooled, white solid was collected, rinsed with EtOAc and dried in vacuo to provide the title compound 1.61 g (6.2 mmol) in 36% yield. |
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