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ChemicalBook--->CAS DataBase List--->115461-40-0

115461-40-0

115461-40-0 Structure

115461-40-0 Structure
IdentificationBack Directory
[Name]

19(S)-HETE
[CAS]

115461-40-0
[Synonyms]

19(S)-HETE
19(S)-HETE Exclusive
XFUXZHQUWPFWPR-DZBJBCEBSA-N
19(S)-hydroxy-5(Z),8(Z),11(Z),14(Z)-eicosatetraenoic acid
5,8,11,14-Eicosatetraenoic acid, 19-hydroxy-, (5Z,8Z,11Z,14Z,19S)-
[Molecular Formula]

C20H32O3
[MDL Number]

MFCD18427931
[MOL File]

115461-40-0.mol
[Molecular Weight]

320.47
Chemical PropertiesBack Directory
[Boiling point ]

477.3±45.0 °C(Predicted)
[density ]

0.984±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMF: 20 mg/ml; DMSO: 20 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 0.5 mg/ml
[pka]

4.75±0.10(Predicted)
Hazard InformationBack Directory
[Description]

19-HETE is one of the major cytochrome P450 (CYP450) metabolites of arachidonic acid that is released from the kidney in response to angiotensin II. When formed by the CYP2E1 isoform, 19-HETE is composed of 70% and 30% of the (S) and (R) stereoisomers, respectively. Both 19(S)- and 19(R)-HETE are potent vasodilators of renal preglomerular vessels. 19(S)-HETE stimulates both renal sodium-potassium ATPase and volume absorption in the rabbit proximal straight tubule.
[Definition]

ChEBI:19(S)-HETE is a HETE having a (19S)-hydroxy group and all-cis double bonds at positions 5, 8, 11 and 14. It has a role as a mouse metabolite. It is functionally related to an icosa-5,8,11,14-tetraenoic acid and an arachidonic acid.
[storage]

Store at -20°C
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