Identification | Back Directory | [Name]
ML077 | [CAS]
1135304-61-8 | [Synonyms]
ML077 ML077 (VU0255011) Acetamide, N-methyl-N-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]- | [Molecular Formula]
C17H16N4OS2 | [MOL File]
1135304-61-8.mol | [Molecular Weight]
356.47 |
Hazard Information | Back Directory | [Description]
ML-077, also known as VU0255011, is a highly selective, potent, saline soluble, "best in class" KCC2 antagonist for high fidelity in vitro studies on KCC2 function with IC(50)=537 nM. ML-077 is cell permeable and exhibits submicromolar potency, and shows greater than 10-fold selectivity over other closely related NKCC transporters. | [Definition]
ChEBI:N-methyl-N-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]acetamide is a member of pyridazines and a ring assembly. |
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Company Name: |
Key Organics Ltd.
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Tel: |
+44 (0) 1840-212137 |
Website: |
www.keyorganics.net |
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