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ChemicalBook--->CAS DataBase List--->1135304-61-8

1135304-61-8

1135304-61-8 Structure

1135304-61-8 Structure
IdentificationBack Directory
[Name]

ML077
[CAS]

1135304-61-8
[Synonyms]

ML077
ML077 (VU0255011)
Acetamide, N-methyl-N-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]-
[Molecular Formula]

C17H16N4OS2
[MOL File]

1135304-61-8.mol
[Molecular Weight]

356.47
Hazard InformationBack Directory
[Description]

ML-077, also known as VU0255011, is a highly selective, potent, saline soluble, "best in class" KCC2 antagonist for high fidelity in vitro studies on KCC2 function with IC(50)=537 nM. ML-077 is cell permeable and exhibits submicromolar potency, and shows greater than 10-fold selectivity over other closely related NKCC transporters.
[Definition]

ChEBI:N-methyl-N-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]acetamide is a member of pyridazines and a ring assembly.
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