| Identification | Back Directory | [Name]
TRANS-(1S 3R)-ACPD | [CAS]
111900-32-4 | [Synonyms]
cb1712
3R)-ACPD
ACPD (1S,3R)-
1-amino-1,3-dicarboxycyclopentane
1-amino-1,3-cyclopentanedicarboxylicacid
1-aminocyclopentane-1s,3r-dicarboxylicacid
1-amino-3-cyclopentanedicarboxylicaci(1s-cis)-
TRANS-(1S,3R)-APCD >97% AGONIST FOR META BOTRO
1,3-Cyclopentanedicarboxylic acid, 1-amino-, (1S,3R)- | [Molecular Formula]
C7H11NO4 | [MDL Number]
MFCD00153760 | [MOL File]
111900-32-4.mol | [Molecular Weight]
173.17 |
| Chemical Properties | Back Directory | [Melting point ]
248 °C (decomp)(Solv: ethanol (64-17-5); water (7732-18-5)) | [alpha ]
-6.9 (D/20℃) (c=1, H2O)-10.1 (D/20℃) (c=1, 6M HCl) | [Boiling point ]
352.7±42.0 °C(Predicted) | [density ]
1.452±0.06 g/cm3(Predicted) | [storage temp. ]
Store at RT | [solubility ]
ethanol: 0.24 mg/mL | [form ]
solid | [pka]
2.11±0.40(Predicted) | [color ]
white | [Water Solubility ]
Soluble to 30 mM in water |
| Hazard Information | Back Directory | [Uses]
trans-(1S,3R)-ACPD is a rigid glutamate analog and mGluR activator. | [Biological Activity]
Active isomer of (±)-trans-ACPD ((?-1-Aminocyclopentane-trans-1,3-dicarboxylic acid ). Agonist at both group I and II mGlu receptors (EC 50 values are 5, 15, 42 and 60 μ M at mGluR 2 , mGluR 5 , mGluR 1 and mGluR 6 respectively). | [storage]
Store at RT |
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