| Identification | Back Directory | [Name]
2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE | [CAS]
111686-79-4 | [Synonyms]
fpl12924aa
pr934-423a
RemacemideHCl
REMACEMIDE HYDROCHLORIDE
2-AMino-N-(1,2-diphenylpropan-2-yl)acetaMide hydrochloride
2-AMINO-N-(1-METHYL-1,2-DIPHENYLETHYL)ACETAMIDE HYDROCHLORIDE
2-diphenylethyl)acetamidemonohydrochloride(+-)-2-amino-n-(1-methyl-
2-amino-n-(1-methyl-1,2-diphenylethyl)-,monohydrochloride,(+-)-acetamid | [Molecular Formula]
C17H21ClN2O | [MDL Number]
MFCD00882179 | [MOL File]
111686-79-4.mol | [Molecular Weight]
304.81 |
| Chemical Properties | Back Directory | [Melting point ]
253-254° | [storage temp. ]
room temp | [solubility ]
H2O: >10mg/mL | [form ]
powder | [color ]
white to beige | [Water Solubility ]
Soluble to 100 mM in water |
| Hazard Information | Back Directory | [Uses]
Anticonvulsant (neuroprotective). | [Biological Activity]
Non-competitive NMDA receptor antagonist; blocks ion channel and allosteric modulatory site (IC 50 = 8-68 mM). Anticonvulsant in vivo and metabolizes to a more potent desglycine analog. Weakly blocks voltage-dependent Na + channels (IC 50 = 161 mM). | [Biochem/physiol Actions]
Remacemide HCl is a low affinity NMDA antagonist with anticonvulsant properties. Remacemide also been shown to block voltage-dependent sodium channels. | [storage]
Desiccate at RT |
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