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ChemicalBook--->CAS DataBase List--->1115910-36-5

1115910-36-5

1115910-36-5 Structure

1115910-36-5 Structure
IdentificationBack Directory
[Name]

icFSP1
[CAS]

1115910-36-5
[Synonyms]

icFSP1
[Molecular Formula]

C26H25N3O5
[MOL File]

1115910-36-5.mol
[Molecular Weight]

459.49
Chemical PropertiesBack Directory
[density ]

1.251±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
[storage temp. ]

-10 to -25°C
[solubility ]

DMSO: 2mg/mL, clear
[form ]

Solid
[pka]

13.608±0.70(predicted)
[color ]

White to yellow
Hazard InformationBack Directory
[Biological Activity]

Selective and efficacious in vivo inhibitor of ferroptosis-suppressor-protein 1 (FSP1); ferroptosis inducer.

icFSP1 is a selective and efficacious in vivo inhibitor of ferroptosis-suppressor-protein 1 (FSP1). icFSP1 triggers subcellular relocalization of FSP1 from the membrane and initiate FSP1 reversible aggregation into liquid droplet-like structures before ferroptosis initiation. It synergizes with ferroptosis inducing agents to potentiate the ferroptotic cell death response.
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