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ChemicalBook--->CAS DataBase List--->1101113-39-6

1101113-39-6

1101113-39-6 Structure

1101113-39-6 Structure
IdentificationBack Directory
[Name]

MitoTEMPOL
[CAS]

1101113-39-6
[Synonyms]

MitoTEMPOL
[Molecular Formula]

C32H42BrNO2P*
[MOL File]

1101113-39-6.mol
[Molecular Weight]

583.559
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 10 mg/ml
[form ]

A solid
Hazard InformationBack Directory
[Description]

MitoTEMPOL is a mitochondria-targeting superoxide dismutase mimetic that reduces mitochondrial O2- to H2O2. Like the related compound MitoTEMPO , MitoTEMPOL combines an antioxidant moiety (here, TEMPOL, also known as 4-hydroxy-TEMPO) with the lipophilic cation triphenylphosphonium, which allows it to pass through lipid bilayers and accumulate in mitochondria. MitoTEMPOL has been used to elucidate the role of mitochondria-derived superoxide in mitochondrial, cellular, and whole animal signaling.
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