| Identification | Back Directory | [Name]
lactosyl lysosphingolipid | [CAS]
109785-20-8 | [Synonyms]
Lactosyl-C18-sphingosine
lactosyl lysosphingolipid
lactosyl-beta-sphingosine
Lactosylsphingosine (d18:1)
Lactosyl(β) Sphingosine (d18:1)
Lactosyl(ss) Sphingosine (d18:1)
Lyso-Lactosylceramide (synthetic)
Lactosyl(beta) Sphingosine (d18:1)
D-lactosyl-1-1'-D-erythro-sphingosine
D-lactosyl-?1-1'-D-erythro-sphingosine
Lacsph d18:1 (Galb1,4GlcbSphingolipids)
Lactosylsphingosine (d18:1) (synthetic)
β-D-Glucopyranoside, (2S,3R,4E)-2-amino-3-hydroxy-4-octadecen-1-yl 4-O-β-D-galactopyranosyl-
2-[6-[(E,2S,3R)-2-amino-3-hydroxyoctadec-4-enoxy]-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol | [Molecular Formula]
C30H57NO12 | [MDL Number]
MFCD07374300 | [MOL File]
109785-20-8.mol | [Molecular Weight]
623.773 |
| Chemical Properties | Back Directory | [Boiling point ]
845.8±65.0 °C(Predicted) | [density ]
1.27±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
Chloroform:Methanol:Water (2:1:0.1): soluble; DMSO: soluble; Water: soluble | [form ]
A solid | [pka]
11.74±0.45(Predicted) | [BRN ]
5680460 |
| Hazard Information | Back Directory | [Description]
Lactosylsphingosine is a bioactive sphingolipid and a form of lactosylceramide that is lacking the fatty acyl group. Lyso-lactosylceramide (1-50 μM) reduces viability of human neutrophils in a concentration-dependent manner. Unlike lactosylceramide, Lactosylsphingosine has no effect on protein synthesis and cell proliferation in cardiomyocytes. Lactosylsphingosine is a precursor in the synthesis of lyso-ganglioside GM3. [Matreya, LLC. Catalog No. 2088] | [Uses]
Lactosyl(β) Sphingosine (d18:1) or D-lactosyl-β1-1′-D-erythro-sphingosine has been used as an internal standard for the quantification of psychosine?using tandem mass spectrometry. It may be used to screen lipids that rapidly and reversibly alter?transepithelial?electrical resistance (TER) or tight junction (TJ) permeability in epithelial?tissue. It may also be used as a standard to determine the extent of recovery of lyso-neutral glycosphingolipids (lyso-n-GSLs) from the Sephadex column. | [General Description]
Lactosyl sphingosine?is a glycosylsphingosine (Lyso-GSL), which is found in bovine brain white matter extract. | [Biochem/physiol Actions]
Lactosyl sphingosine?exhibits better hemolytic activity than lysolecithin. |
|
| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
Alfa Chemistry
|
| Tel: |
1-516-6625404 |
| Website: |
https://www.alfa-chemistry.com |
| Company Name: |
BOC Sciences
|
| Tel: |
16314854226 |
| Website: |
www.approvedhomemanagement.com/showsupplierproductslist1701258/0.htm |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
|