| Identification | Back Directory | [Name]
2-(4-(5-(3,4-Diethoxyphenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-ylamino)ethanolhydrochloride | [CAS]
1094042-01-9 | [Synonyms]
CS-2567
CYM 5442
CYM 5442 HCl
CYM 5442;CYM-5442
CYM5442 , 1094042-01-9
CYM 5442 hydrochloride
2-(4-(5-(3,4-diethoxyphenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-ylamino)ethanol
Ethanol, 2-[[4-[5-(3,4-diethoxyphenyl)-1,2,4-oxadiazol-3-yl]-2,3-dihydro-1H-inden-1-yl]amino]-
2-(4-(5-(3,4-Diethoxyphenyl)-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-ylamino)ethanolhydrochloride | [Molecular Formula]
C23H27N3O4 | [MDL Number]
MFCD12912402 | [MOL File]
1094042-01-9.mol | [Molecular Weight]
409.48 |
| Chemical Properties | Back Directory | [Boiling point ]
617.5±65.0 °C(Predicted) | [density ]
1.27±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
DMSO: >5mg/mL | [form ]
A crystalline solid | [pka]
14.73±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
CYM 5442 is an extracellular lipid mediator whose major effects are mediated by G-protein-coupled receptors. These are important for vascular development. | [Definition]
ChEBI: CYM5442 is an oxadiazole and a ring assembly. | [Biochem/physiol Actions]
CYM-5442 is a highly-selective S1P1 (Spingosine 1-Phosphate Receptor 1) agonist that activates S1P1-dependent pathways in vitro and to levels of full efficacy in vivo through a hydrophobic pocket, separable from the orthosteric site of S1P binding that is headgroup dependent. This is a different site from those involved in the activities of other agonists such as FTY720 and SEW2871. |
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