| Identification | Back Directory | [Name]
Morphothiadin | [CAS]
1092970-12-1 | [Synonyms]
GLS4
(GLS 4
Morphothiadin
GLS 4(Morphothiadin)
Morphothiadin (GLS4)
Morphothiadin USP/EP/BP
Morphothiadin,inhibit,HBV,Inhibitor,GLS-4,GLS 4,Hepatitis B virus
5-Pyrimidinecarboxylic acid, 4-(2-bromo-4-fluorophenyl)-1,4-dihydro-6-(4-morpholinylmethyl)-2-(2-thiazolyl)-, ethyl ester | [Molecular Formula]
C21H22BrFN4O3S | [MDL Number]
MFCD30738320 | [MOL File]
1092970-12-1.mol | [Molecular Weight]
509.39 |
| Chemical Properties | Back Directory | [Boiling point ]
577.2±60.0 °C(Predicted) | [density ]
1.58±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMF: 12 mg/ml; DMSO: 1 mg/ml; Ethanol: Slightly soluble; PBS (pH 7.2): 0.3 mg/ml | [form ]
A solid | [pka]
8.38±0.10(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
Morphothiadin, is a potent inhibitor on the replication of both wild-type and adefovir-resistant HBV with an IC50 of 12 nM. It strongly inhibits virus accumulation in the supernatant of HepAD38 cells at 25 nM to 100 nM (P<0.02). | [storage]
Store at -20°C |
|
| Company Name: |
Twochem Co.Ltd.
|
| Tel: |
021-58111628 15800915896 |
| Website: |
cn.twochem.com |
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