| Identification | Back Directory | [Name]
12-KETE | [CAS]
108437-64-5 | [Synonyms]
12-KETE
12-OXOETE
GURBRQGDZZKITB-VXBMJZGYSA-N
12-OxoETE Lipid Maps MS Standard
12-OXO-5Z,8Z,10E,14Z-EICOSATETRAENOIC ACID
5,8,10,14-Eicosatetraenoic acid, 12-oxo-, (5Z,8Z,10E,14Z)- | [Molecular Formula]
C20H30O3 | [MDL Number]
MFCD00216130 | [MOL File]
108437-64-5.mol | [Molecular Weight]
318.45 |
| Hazard Information | Back Directory | [Uses]
12-OxoETE is synthesized by human platelets and Aplysia nervous tissue after incubation with arachidonic acid. Microsomal fractions of various tissues will reduce 12-oxoETE to 12(S)-HETE or a mixture of 12(S)- and 12(R)-HETE. 12-OxoETE induces a rapid, dose dependent increase of cytoplasmic free calcium via an Leukotriene B4 receptor or a common activation sequence. | [Definition]
ChEBI: An oxoicosatetraenoic acid having a 12-oxo group; and (5Z)-, (8Z), (10E)- and (14Z)-double bonds. | [storage]
Store at -20°C |
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