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PD 120697 is a dopamine antagonist. It is a novel class of compounds with central dopamine agonist properties. It has been identified as orally active dopamine (DA) agonists with pronounced central nervous system effects in tests that include [3H]-haloperidol and [3H]-N-propylnorapomorphine binding, inhibition of striatal DA synthesis, inhibition of DA neuronal firing, inhibition of spontaneous locomotor activity, and reversal of reserpine-induced depression in rats. |
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Company Name: |
BOC Sciences
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Tel: |
16314854226 |
Website: |
www.bocsci.com |
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