| Identification | Back Directory | [Name]
4-bromo-phenyl-(4-phenyl-thiazol-2-yl)-amine | [CAS]
108237-91-8 | [Synonyms]
RCGD423
RCGD 432
2-Thiazolamine, N-(4-bromophenyl)-4-phenyl-
4-bromo-phenyl-(4-phenyl-thiazol-2-yl)-amine | [Molecular Formula]
C15H11BrN2S | [MDL Number]
MFCD01123615 | [MOL File]
108237-91-8.mol | [Molecular Weight]
331.23 |
| Chemical Properties | Back Directory | [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [solubility ]
DMSO:34.0(Max Conc. mg/mL);102.6(Max Conc. mM)
Ethanol:34.0(Max Conc. mg/mL);102.6(Max Conc. mM) | [form ]
A solid | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Biological Activity]
RCGD-423 is a Glycoprotein 130 (gp130, IL6ST, IL6-beta, CD130) signaling regulator that regulates cartilage growth and differentiation. | [in vitro]
RCGD423 is a gp130 modulator, which prevents articular cartilage degeneration and promotes repair. | [in vivo]
RCGD423 greatly reduces chondrocyte hypertrophy, loss and degeneration while increasing chondrocyte proliferation beyond that observed in response to injury in a rat partial meniscectomy model. Moreover, RCGD 423 improves cartilage healing in a rat full-thickness osteochondral defect model, | [target]
| [storage]
Store at -20°C |
|
| Company Name: |
Twochem Co.Ltd.
|
| Tel: |
021-58111628 15800915896 |
| Website: |
cn.twochem.com |
| Company Name: |
DC Chemicals
|
| Tel: |
021-58447131 13564518121 |
| Website: |
http://www.approvedhomemanagement.com/ShowSupplierProductsList927327/0.htm |
|